Structure of PDB 4e3w Chain A

Receptor sequence

>4e3wA (length=329) Species: 376619 (Francisella tularensis subsp. holarctica LVS) [Search protein sequence]

SKLIFVSMITRNGDRAPFANIENANYSWGTELSELTPIGMNQEYNLGLQL
RKRYIDKFGLLPEHYVDQSIYVLSSHTNRTVVSAQSLLMGLYPAGTGPLI
GDGDPAIKDRFQPIPIMTLSADSRLIQFPYEQYLAVLKKYVYNSPEWQNK
TKEAAPNFAKWQQILGNRISGLNDVITVGDVLIVAQAHGKPLPKGLSQED
ADQIIALTDWGLAQQFKSQKVSYIMGGKLTNRMIEDLNNAVNGKSKYKMT
YYSGHALTLLEVMGTLGVPLDTAPGYASNLEMELYKDGDIYTVKLRYNGK
YVKLPIMDKNNSCSLDALNKYMQSINEKF

3D structure

PDB

4e3w Proline: Mother Nature's cryoprotectant applied to protein crystallography.

Chain

Resolution

1.75 Å

3D
structure

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Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)
BS01	SO4	A	R16 N17 R20 R84 H260 A261	R11 N12 R15 R79 H255 A256
BS02	SO4	A	F23 R84	F18 R79
BS03	PRO	A	F23 Y135	F18 Y130

External links

PDB	RCSB:4e3w, PDBe:4e3w, PDBj:4e3w
PDBsum	4e3w
PubMed	22868767

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