Structure of PDB 4e2d Chain A

Receptor sequence
>4e2dA (length=377) Species: 5693 (Trypanosoma cruzi) [Search protein sequence]
ATFPELLRPLKLGRYTLRNRIIMAPLTRCQATEDGHVPRTESMLKYYEDR
ASAGLIIAEATMVQPNYTGFLTEPGIYSDAQIEEWRKIVDAVHKKGGLIF
LQLIHAGRAGIPEKILQQPKSDQDPLAGRLLAASAIPIKDHRIPAYFAAS
GEKETYGVPEELTDDEVRNGIIPLFVEGAKNAIFKAGFDGVEIHGANGYL
LDAFFRESSNKRQSGPYAGTTIDTRCQLIYDVTKSVCDAVGSDRVGLRIS
PLNGVHGMIDSNPEALTKHLCKKIEPLSLAYLHYLRGDMVNQQIGDVVAW
VRGSYSGVKISNLRYDFEEADQQIREGKVDAVAFGAKFIANPDLVERAQH
DWPLNEPRPETYYTRTAVGYNDYPTYN
3D structure
PDB4e2d High resolution crystal structure and in solution studies of the Old Yellow Enzyme from Trypanosoma cruzi: Insights into oligomerization, enzyme dynamics and specificity
ChainA
Resolution1.997 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) T28 H195 N198 Y200 R249 H257
Catalytic site (residue number reindexed from 1) T27 H194 N197 Y199 R248 H256
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FMN A P26 L27 T28 A61 Q103 H195 N198 R249 N313 R315 G336 A337 Y363 Y364 P25 L26 T27 A60 Q102 H194 N197 R248 N312 R314 G335 A336 Y362 Y363
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0010181 FMN binding
GO:0016491 oxidoreductase activity
Cellular Component
GO:0005737 cytoplasm

View graph for
Molecular Function
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Cellular Component
External links
PDB RCSB:4e2d, PDBe:4e2d, PDBj:4e2d
PDBsum4e2d
PubMed
UniProtQ2TJB8

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