Structure of PDB 4e19 Chain A

Receptor sequence
>4e19A (length=133) Species: 64091 (Halobacterium salinarum NRC-1) [Search protein sequence]
GGRVHAYFDGASRGNPGPAAVGWVLVSGDGGIVAEGGDTIGRATNNQAEY
DALIAALEAAADFGFDDIELRGDSQLVEKQLTGAWDTNDPDLRRKRVRAR
ELLTGFDDWSITHVPRATNERADALANEALDDA
3D structure
PDB4e19 Crystal structure of RNase H1 from halophilic archaeon Halobacterium salinarum NRC-1
ChainA
Resolution1.41 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.26.4: ribonuclease H.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MN A D75 E115 D139 D9 E49 D73
BS02 MN A D75 D189 D9 D123
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0003723 RNA binding
GO:0004519 endonuclease activity
GO:0004523 RNA-DNA hybrid ribonuclease activity
GO:0004527 exonuclease activity
GO:0046872 metal ion binding
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Cellular Component
External links
PDB RCSB:4e19, PDBe:4e19, PDBj:4e19
PDBsum4e19
PubMed
UniProtQ9HSF6|RNH_HALSA Ribonuclease HI (Gene Name=rnhA)

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