Structure of PDB 4e0i Chain A

Receptor sequence
>4e0iA (length=152) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence]
EGLSGRKIIYDEDGKPSRSCNTLLDFQYVTGKISELMPGSRTYRKVDPPD
VEQLGRSSWTLLHSVAASYPAQPTDQQKGEMKQFLNIFSHIYPCNWSAKD
FEKYIRENAPQVESREELGRWMCEAHNKVNKKLRKPKFDCNFWEKRWKDG
WD
3D structure
PDB4e0i Structure of yeast sulfhydryl oxidase erv1 reveals electron transfer of the disulfide relay system in the mitochondrial intermembrane space
ChainA
Resolution3.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.8.3.2: thiol oxidase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FAD A E88 G91 R92 W95 H99 Y128 S133 F137 C159 H162 N163 V165 N166 L169 K171 F174 R182 W183 E52 G55 R56 W59 H63 Y92 S97 F101 C123 H126 N127 V129 N130 L133 K135 F138 R146 W147
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0016491 oxidoreductase activity
GO:0016971 flavin-dependent sulfhydryl oxidase activity
GO:0016972 thiol oxidase activity
GO:0050660 flavin adenine dinucleotide binding
Biological Process
GO:0006879 intracellular iron ion homeostasis
GO:0034599 cellular response to oxidative stress
GO:0045041 protein import into mitochondrial intermembrane space
Cellular Component
GO:0005739 mitochondrion
GO:0005758 mitochondrial intermembrane space

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Cellular Component
External links
PDB RCSB:4e0i, PDBe:4e0i, PDBj:4e0i
PDBsum4e0i
PubMed22910915
UniProtP27882|ERV1_YEAST Mitochondrial FAD-linked sulfhydryl oxidase ERV1 (Gene Name=ERV1)

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