Structure of PDB 4dwa Chain A

Receptor sequence
>4dwaA (length=154) Species: 268305 (Bovine viral diarrhea virus 1-CP7) [Search protein sequence]
ENITQWNLQDNGTEGIQRAMFQRGVNRSLKGIWPEKICTGVPSHLATDTE
LKAIHGMMDASEKTNYTCCRLQRHEWNKHGWCNWYNIEPWILLMNKTQAN
LTEGRECAVTCRYDRDSDLNVVTQARDSPTPLTGCKKGKNFSFAGILVQG
PCNF
3D structure
PDB4dwa Crystal Structure of the Pestivirus Envelope Glycoprotein E(rns) and Mechanistic Analysis of Its Ribonuclease Activity.
ChainA
Resolution3.01 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.48: RNA-directed RNA polymerase.
3.4.21.113: pestivirus NS3 polyprotein peptidase.
3.4.22.-
3.6.1.15: nucleoside-triphosphate phosphatase.
3.6.4.13: RNA helicase.
4.6.1.19: ribonuclease T2.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna A N9 K32 A62 R72 N7 K30 A60 R70
BS02 BMA A N88 P91 N86 P89
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0033897 ribonuclease T2 activity

View graph for
Molecular Function
External links
PDB RCSB:4dwa, PDBe:4dwa, PDBj:4dwa
PDBsum4dwa
PubMed22579253
UniProtQ96662|POLG_BVDVC Genome polyprotein

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