Structure of PDB 4dw5 Chain A

Receptor sequence
>4dw5A (length=158) Species: 268305 (Bovine viral diarrhea virus 1-CP7) [Search protein sequence]
ENITQWNLQDNGTEGIQRAMFQRGVNRSLHGIWPEKICTGVPSHLATDTE
LKAIHGMMDASEKTNYTCCRLQRHEWNKHGWCNWYNIEPWILLMNKTQAN
LTEGPLRECAVTCRYDRDSDLNVVTQARDSPTPLTGCKKGKNFSFAGILV
QGPCNFEI
3D structure
PDB4dw5 Crystal Structure of the Pestivirus Envelope Glycoprotein E(rns) and Mechanistic Analysis of Its Ribonuclease Activity.
ChainA
Resolution2.21 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.48: RNA-directed RNA polymerase.
3.4.21.113: pestivirus NS3 polyprotein peptidase.
3.4.22.-
3.6.1.15: nucleoside-triphosphate phosphatase.
3.6.4.13: RNA helicase.
4.6.1.19: ribonuclease T2.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CSQ A N9 H32 A62 S63 R72 L73 Q129 N7 H30 A60 S61 R70 L71 Q126
BS02 CSV A N9 H32 A62 R72 Q129 N7 H30 A60 R70 Q126
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0033897 ribonuclease T2 activity

View graph for
Molecular Function
External links
PDB RCSB:4dw5, PDBe:4dw5, PDBj:4dw5
PDBsum4dw5
PubMed22579253
UniProtQ96662|POLG_BVDVC Genome polyprotein

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