Structure of PDB 4dvg Chain A

Receptor sequence
>4dvgA (length=164) Species: 5759 (Entamoeba histolytica) [Search protein sequence]
LKIVVVGDGAVGKTCLLLAFSKGEIPTAYVPTVFENFSHVMKYKNEEFIL
HLWDTAGQEEYDRLRPLSYADSDVVLLCFAVNNRTSFDNISTKWEPEIKH
YIDTAKTVLVGLKVDLRKDGSDDVTKQEGDDLCQKLGCVAYIEASSVAKI
GLNEVFEKSVDCIF
3D structure
PDB4dvg Entamoeba histolytica Rho1 Regulates Actin Polymerization through a Divergent, Diaphanous-Related Formin.
ChainA
Resolution2.604 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.5.2: small monomeric GTPase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GSP A A30 G32 K33 T34 C35 Y49 T52 G77 K133 D135 L136 S165 S166 V167 A10 G12 K13 T14 C15 Y29 T32 G57 K113 D115 L116 S145 S146 V147
BS02 MG A T34 T52 T14 T32
Gene Ontology
Molecular Function
GO:0003924 GTPase activity
GO:0005525 GTP binding
Biological Process
GO:0007264 small GTPase-mediated signal transduction

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Molecular Function
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Biological Process
External links
PDB RCSB:4dvg, PDBe:4dvg, PDBj:4dvg
PDBsum4dvg
PubMed23050667
UniProtP31021|RHO1_ENTH1 Ras-like GTP-binding protein RHO1 (Gene Name=RHO1)

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