Structure of PDB 4dtl Chain A

Receptor sequence
>4dtlA (length=356) Species: 666 (Vibrio cholerae) [Search protein sequence]
ATPDFPTHFPKSSIGIENELAGLVVAMPANSAQKFGYVKSAQGDALFMLT
KDMNQGSYQRPPSLQDGKNYQNWQTHTVELVSYPCEMDDKAAVETRKQAM
LWLATHFTTHIDQSNHQPLAPIQSEDGRFVIEITNAKHVIAAGNGISAES
QGQTITMTPSGQQATVGVAAKGFGTSATPELRLLESAPWYQKSLKSQFAS
LTSAENLDDKELAANVFAYLTSIYLKTAELAKKFGIYINEWDPMSEQITP
NANGLTDPKVKNAWEILPRTKPSKIVEILSKSDAKAVMKHIKPQLQSRYS
ESLSKNVFQYFQDGGEVAGHGINNATVGDKHSPELAILFEFRTVPNELQS
YLPKTE
3D structure
PDB4dtl Structure of a VgrG Vibrio cholerae toxin ACD domain in complex with ATP and Mn++
ChainA
Resolution2.39 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 6.3.2.-
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 ATP A F4 S12 G14 I15 E16 S81 P83 T164 L337 F5 S13 G15 I16 E17 S82 P84 T165 L338
BS02 MN A E16 Q162 E339 E17 Q163 E340
BS03 MN A E16 E78 E17 E79
Gene Ontology
Biological Process
GO:0007015 actin filament organization

View graph for
Biological Process
External links
PDB RCSB:4dtl, PDBe:4dtl, PDBj:4dtl
PDBsum4dtl
PubMed
UniProtA0A0H3AIG7|VGRG1_VIBC3 Actin cross-linking toxin VgrG1 (Gene Name=vgrG1)

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