Structure of PDB 4drz Chain A

Receptor sequence
>4drzA (length=160) Species: 9606 (Homo sapiens) [Search protein sequence]
YNYSYIFKYIIIGDMGVGKSCLLHQFTEKKCPHTIGVEFGTRIIEVSGQK
IKLQIWDTAAVTRSYYRGAAGALMVYDITRRSTYNHLSSWLTDARNLTNP
NTVIILIGNKADLEAQRDVTYEEAKQFAEENGLLFLEASAKTGENVEDAF
LEAAKKIYQN
3D structure
PDB4drz Crystal structure of human RAB14
ChainA
Resolution2.3 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 3.6.5.2: small monomeric GTPase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GDP A G21 V22 G23 K24 S25 C26 N124 K125 D127 L128 S154 A155 K156 G16 V17 G18 K19 S20 C21 N109 K110 D112 L113 S139 A140 K141
BS02 CA A S25 D66 S20 D57
Gene Ontology
Molecular Function
GO:0003924 GTPase activity
GO:0005525 GTP binding
Biological Process
GO:0006895 Golgi to endosome transport
GO:0032456 endocytic recycling
GO:0042742 defense response to bacterium
GO:0090382 phagosome maturation
Cellular Component
GO:0005802 trans-Golgi network
GO:0045335 phagocytic vesicle
GO:0055037 recycling endosome

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:4drz, PDBe:4drz, PDBj:4drz
PDBsum4drz
PubMed
UniProtP61106|RAB14_HUMAN Ras-related protein Rab-14 (Gene Name=RAB14)

[Back to BioLiP]