Structure of PDB 4dr0 Chain A

Receptor sequence
>4dr0A (length=290) Species: 1423 (Bacillus subtilis) [Search protein sequence]
MTKIYDAANWSKHEDDFTQMFYNQNVKQFWLPEEIALNGDLLTWKYLGKN
EQDTYMKVLAGLTLLDTEQGNTGMPIVAEHVDGHQRKAVLNFMAMMENAV
HAKSYSNIFMTLAPTETINEVFEWVKQNKYLQKKAQMIVGLYKAIQKDDE
ISLFKAMVASVYLESFLFYSGFYYPLYFYGQGKLMQSGEIINLILRDEAI
HGVYVGLLAQEIYNKQTEEKKAELREFAIDLLNQLYENELEYTEDLYDQV
GLSHDVKKFIRYNANKALMNLGFDPYFEEEDINPIVLNGL
3D structure
PDB4dr0 The Dimanganese(II) Site of Bacillus subtilis Class Ib Ribonucleotide Reductase.
ChainA
Resolution1.9 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) Y105 D197
Catalytic site (residue number reindexed from 1) Y105 D197
Enzyme Commision number 1.17.4.1: ribonucleoside-diphosphate reductase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MN A E97 E164 E198 H201 E97 E164 E198 H201
BS02 MN A D66 E97 H101 E198 D66 E97 H101 E198
Gene Ontology
Molecular Function
GO:0004748 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor
GO:0016491 oxidoreductase activity
GO:0046872 metal ion binding
Biological Process
GO:0009263 deoxyribonucleotide biosynthetic process
Cellular Component
GO:0005971 ribonucleoside-diphosphate reductase complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4dr0, PDBe:4dr0, PDBj:4dr0
PDBsum4dr0
PubMed22443445
UniProtP50621|RIR2_BACSU Ribonucleoside-diphosphate reductase subunit beta (Gene Name=nrdF)

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