Structure of PDB 4dow Chain A

Receptor sequence
>4dowA (length=157) Species: 10090 (Mus musculus) [Search protein sequence]
TFSWVGRPLPNRKQFQQMYREICMKINDGSEIHIKVGQFVLIQGEDNKKP
YVAKLIELFQNGAEVPPKKCARVQWFVRFLEIPVSKRHLLGRSPPAQEIF
WYDCSDWDNKINVETIIGPVQVVALAPEEVIPVDQKSEETLFVKLSWNKK
DFAPLPP
3D structure
PDB4dow The BAH domain of ORC1 links H4K20me2 to DNA replication licensing and Meier-Gorlin syndrome.
ChainA
Resolution1.95 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A Q55 E57 Y63 W87 E93 S117 D118 W119 D120 E126 T127 Q43 E45 Y51 W75 E81 S105 D106 W107 D108 E114 T115
BS02 peptide A P22 R32 P10 R20
Gene Ontology
Molecular Function
GO:0003682 chromatin binding

View graph for
Molecular Function
External links
PDB RCSB:4dow, PDBe:4dow, PDBj:4dow
PDBsum4dow
PubMed22398447
UniProtQ9Z1N2|ORC1_MOUSE Origin recognition complex subunit 1 (Gene Name=Orc1)

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