Structure of PDB 4dmg Chain A

Receptor sequence
>4dmgA (length=385) Species: 300852 (Thermus thermophilus HB8) [Search protein sequence]
MLGPVLRLVVKAGKERKLRNFYPNLYRDEIAAPPEGVGVAEAVDAEGHFL
AVGYYDPRSRVPFRAFRFDPGPLNRAFFQGRFARALRRRQGLGESHRLVH
GEADGLPGLVVDRFGEVLVLQVRSRGMEALREVWLPALLEVVAPKGVYER
SDVEARRQEGLPERVGVVYGEVPEVLEVEEDGLRFPIPLALAQKTGYYLD
QRENRRLFEAMVRPGERVLDVYSYVGGFALRAARKGAYALAVDKDLEALG
VLDQAALRLGLRVDIRHGEALPTLRGLEGPFHHVLLDPPTLVKRPEELPA
MKRHLVDLVREALRLLAEEGFLWLSSCSYHLRLEDLLEVARRAAADLGRR
LRVHRVTYQPEDHPWSLHIPESLYLKTLVLQDDPL
3D structure
PDB4dmg Identification and Characterization of the Thermus thermophilus 5-Methylcytidine (m5C) Methyltransferase Modifying 23 S Ribosomal RNA (rRNA) Base C1942.
ChainA
Resolution1.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.1.1.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 SAM A Q193 Y198 R205 Y222 S223 Y224 F228 D243 K244 E269 A270 D287 P289 Q193 Y198 R205 Y222 S223 Y224 F228 D243 K244 E269 A270 D287 P289
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0008168 methyltransferase activity
Biological Process
GO:0032259 methylation
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4dmg, PDBe:4dmg, PDBj:4dmg
PDBsum4dmg
PubMed22711535
UniProtQ5SI81|RLM0_THET8 Ribosomal RNA large subunit methyltransferase I (Gene Name=RlmO)

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