Structure of PDB 4dk9 Chain A

Receptor sequence
>4dk9A (length=140) Species: 9606 (Homo sapiens) [Search protein sequence]
WTPPRSPFNLVQETLFHDPWKLLIATIFLNRTSGKMAIPVLWKFLEKYPS
AEVARTADWRDVSELLKPLGLYDLRAKTIVKFSDEYLTKQWKYPIELHGI
GKYGNDSYRIFCVNEWKQVHPEDHKLNKYHDWLWENHEKL
3D structure
PDB4dk9 Crystal Structure of Human Methyl-Binding Domain IV Glycosylase Bound to Abasic DNA.
ChainA
Resolution2.76 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.2.2.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna A R468 M473 P505 G507 L508 Y509 D510 L511 R31 M36 P68 G70 L71 Y72 D73 L74
BS02 dna A L466 N467 R468 S470 G536 G538 K539 Y540 L29 N30 R31 S33 G99 G101 K102 Y103
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003824 catalytic activity
Biological Process
GO:0006281 DNA repair
GO:0006284 base-excision repair

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Molecular Function
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Biological Process
External links
PDB RCSB:4dk9, PDBe:4dk9, PDBj:4dk9
PDBsum4dk9
PubMed22560993
UniProtO95243|MBD4_HUMAN Methyl-CpG-binding domain protein 4 (Gene Name=MBD4)

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