Structure of PDB 4dec Chain A

Receptor sequence
>4decA (length=284) Species: 83332 (Mycobacterium tuberculosis H37Rv) [Search protein sequence]
ALPLDTTWHRPGWTIGELEAAKAGRTISVVLPALNEEATIESVIDSISPL
VDGLVDELIVLDSGSTDDTEIRAIASGARVVSREQALPEVPVRPGKGEAL
WRSLAATSGDIVVFIDSDLINPHPLFVPWLVGPLLTGEGIQLVKSFYRGG
RVTELVARPLLAALRPELGCVLQPLSGEYAASRELLTSLPFAPGYGVEIG
LLIDTFDRLGLDAIAQVNLGVRAHRNRPLDELGAMSRQVIATLLSRCGIP
DSGVGLTQFLPGSDYTRHTWPVSLVDRPPMKVMR
3D structure
PDB4dec Mechanistic insights into the retaining glucosyl-3-phosphoglycerate synthase from mycobacteria.
ChainA
Resolution1.98 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.4.1.266: glucosyl-3-phosphoglycerate synthase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 UDP A P50 A51 L52 E54 S81 G113 K114 D134 S135 D136 Y229 R259 R261 P32 A33 L34 E36 S63 G95 K96 D116 S117 D118 Y195 R225 R227
BS02 MN A D136 H258 D118 H224
BS03 PO4 A Q159 E218 L219 R242 Q141 E184 L185 R208
Gene Ontology
Molecular Function
GO:0000287 magnesium ion binding
GO:0016757 glycosyltransferase activity
GO:0016758 hexosyltransferase activity
GO:0042803 protein homodimerization activity
GO:0046872 metal ion binding
Biological Process
GO:0006011 UDP-glucose metabolic process

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Molecular Function
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Biological Process
External links
PDB RCSB:4dec, PDBe:4dec, PDBj:4dec
PDBsum4dec
PubMed22637481
UniProtP9WMW9|GPGS_MYCTU Glucosyl-3-phosphoglycerate synthase (Gene Name=gpgS)

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