Structure of PDB 4de7 Chain A

Receptor sequence
>4de7A (length=281) Species: 83332 (Mycobacterium tuberculosis H37Rv) [Search protein sequence]
PLDTTWHRPGWTIGELEAAKAGRTISVVLPALNEEATIESVIDSISPLVD
GLVDELIVLDSGSTDDTEIRAIASGARVVSREQALPEVPVRPGKGEALWR
SLAATSGDIVVFIDSDLINPHPLFVPWLVGPLLTGEGIQLVKSFYRGGRV
TELVARPLLAALRPELGCVLQPLSGEYAASRELLTSLPFAPGYGVEIGLL
IDTFDRLGLDAIAQVNLGVRAHRNRPLDELGAMSRQVIATLLSRCGIPDS
GVGLTQFLPGDYTRHTWPVSLVDRPPMKVMR
3D structure
PDB4de7 Mechanistic insights into the retaining glucosyl-3-phosphoglycerate synthase from mycobacteria.
ChainA
Resolution3.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.4.1.266: glucosyl-3-phosphoglycerate synthase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 UDP A P50 A51 L52 E54 S81 K114 P30 A31 L32 E34 S61 K94 PDBbind-CN: -logKd/Ki=4.80,Kd=16uM
Gene Ontology
Molecular Function
GO:0000287 magnesium ion binding
GO:0016757 glycosyltransferase activity
GO:0016758 hexosyltransferase activity
GO:0042803 protein homodimerization activity
GO:0046872 metal ion binding
Biological Process
GO:0006011 UDP-glucose metabolic process

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Molecular Function
View graph for
Biological Process
External links
PDB RCSB:4de7, PDBe:4de7, PDBj:4de7
PDBsum4de7
PubMed22637481
UniProtP9WMW9|GPGS_MYCTU Glucosyl-3-phosphoglycerate synthase (Gene Name=gpgS)

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