Structure of PDB 4dcu Chain A

Receptor sequence
>4dcuA (length=400) Species: 1423 (Bacillus subtilis) [Search protein sequence]
KPVVAIVGRPNVGKSTIFNRIAGERISRIYSSAEWLNYDFNLIDTGGPFL
AQIRQQAEIAMDEADVIIFMVNGREGVTAADEEVAKILYRTKKPVVLAVN
KLYDFYSLGFGEPYPISGTHGLGLGDLLDAVAEHFKNIPETKYNEEVIQF
CLIGRPNVGKSSLVNAMLGEERVIVSNDAVDTSFTYNQQEFVIVDTAGMR
KKGKVYETTEKYSVLRALKAIDRSEVVAVVLDGEEGIIEQDKRIAGYAHE
AGKAVVIVVNKWDAVDKDESTMKEFEENIRDHFQFLDYAPILFMSALTKK
RIHTLMPAIIKASENHSLRVQTNVLNDVIMDAVAMNPTPTHNGSRLKIYY
ATQVSVKPPSFVVFVNDPELMHFSYERFLENRIRDAFGFEGTPIKIFARA
3D structure
PDB4dcu Potassium Acts as a GTPase-Activating Element on Each Nucleotide-Binding Domain of the Essential Bacillus subtilis EngA.
ChainA
Resolution2.0 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) F20 E26
Catalytic site (residue number reindexed from 1) F18 E24
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GDP A N185 G187 K188 S189 S190 K236 N294 K295 D297 S329 A330 L331 N157 G159 K160 S161 S162 K202 N260 K261 D263 S295 A296 L297 MOAD: Kd=8uM
BS02 GDP A N13 G15 K16 S17 T18 N119 K120 S145 G146 N11 G13 K14 S15 T16 N100 K101 S117 G118 MOAD: Kd=8uM
Gene Ontology
Molecular Function
GO:0005525 GTP binding
GO:0043022 ribosome binding
Biological Process
GO:0042254 ribosome biogenesis

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Molecular Function
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Biological Process
External links
PDB RCSB:4dcu, PDBe:4dcu, PDBj:4dcu
PDBsum4dcu
PubMed23056455
UniProtP50743|DER_BACSU GTPase Der (Gene Name=der)

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