Structure of PDB 4dcs Chain A

Receptor sequence
>4dcsA (length=406) Species: 1423 (Bacillus subtilis) [Search protein sequence]
KPVVAIVGRPNVGKSTIFNRIAGERISRIYSSAEWLNYDFNLIDTGGPFL
AQIRQQAEIAMDEADVIIFMVNGREGVTAADEEVAKILYRTKKPVVLAVN
KLMRANIYDFYSLGFGEPYPISGTHGLGLGDLLDAVAEHFKNIPETKYNE
EVIQFCLIGRPNVGKSSLVNAMLGEERVIVSNDAVDTSFTYNQQEFVIVD
TAGMRKKGKVYETTEKYSVLRALKAIDRSEVVAVVLDGEEGIIEQDKRIA
GYAHEAGKAVVIVVNKWDAVDKDESTMKEFEENIRDHFQFLDYAPILFMS
ALTKKRIHTLMPAIIKASENHSLRVQTNVLNDVIMDAVAMNPTPTHNGSR
LKIYYATQVSVKPPSFVVFVNDPELMHFSYERFLENRIRDAFGFEGTPIK
IFARAR
3D structure
PDB4dcs Potassium Acts as a GTPase-Activating Element on Each Nucleotide-Binding Domain of the Essential Bacillus subtilis EngA.
ChainA
Resolution2.25 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) F20 E26
Catalytic site (residue number reindexed from 1) F18 E24
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GDP A N185 V186 G187 K188 S189 S190 K236 N294 K295 D297 S329 L331 N162 V163 G164 K165 S166 S167 K207 N265 K266 D268 S300 L302 MOAD: Kd=8uM
PDBbind-CN: -logKd/Ki=5.10,Kd=8.0uM
Gene Ontology
Molecular Function
GO:0005525 GTP binding
GO:0043022 ribosome binding
Biological Process
GO:0042254 ribosome biogenesis

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Molecular Function
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Biological Process
External links
PDB RCSB:4dcs, PDBe:4dcs, PDBj:4dcs
PDBsum4dcs
PubMed23056455
UniProtP50743|DER_BACSU GTPase Der (Gene Name=der)

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