Structure of PDB 4daj Chain A

Receptor sequence
>4dajA (length=429) Species: 10116,10665 [Search protein sequence]
IWQVVFIAFLTGFLALVTIIGNILVIVAFKVNKQLKTVNNYFLLSLACAD
LIIGVISMNLFTTYIIMNRWALGNLACDLWLSIDYVASNASVMNLLVISF
DRYFSITRPLTYRAKRTTKRAGVMIGLAWVISFVLWAPAILFWQYFVGKR
TVPPGECFIQFLSEPTITFGTAIAAFYMPVTIMTILYWRIYKETEKMNIF
EMLRIDEGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNT
NGVITKDEAEKLFNQDVDAAVRGILRNAKLKPVYDSLDAVRRAALINMVF
QMGETGVAGFTNSLRMLQQKRWDEAAVNLAKSRWYNQTPNRAKRVITTFR
TGTWDAYLIKEAQTLSAILLAFIITWTPYNIMVLVNTFCDSCIPKTYWNL
GYWLCYINSTVNPVCYALCNKTFRTTFKT
3D structure
PDB4daj Structure and dynamics of the M3 muscarinic acetylcholine receptor.
ChainA
Resolution3.4 Å
3D
structure
Catalytic site residues are labeled in the structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Catalytic site (original residue number in PDB) E1011 D1020
Catalytic site (residue number reindexed from 1) E207 D216
Enzyme Commision number 3.2.1.17: lysozyme.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 0HK A D147 Y148 S151 N152 W199 A238 W503 Y506 N507 Y529 C532 D84 Y85 S88 N89 W136 A175 W376 Y379 N380 Y402 C405
Gene Ontology
Molecular Function
GO:0003796 lysozyme activity
GO:0004930 G protein-coupled receptor activity
GO:0016798 hydrolase activity, acting on glycosyl bonds
Biological Process
GO:0007186 G protein-coupled receptor signaling pathway
GO:0009253 peptidoglycan catabolic process
GO:0016998 cell wall macromolecule catabolic process
GO:0031640 killing of cells of another organism
GO:0042742 defense response to bacterium
GO:0044659 viral release from host cell by cytolysis
Cellular Component
GO:0016020 membrane
GO:0030430 host cell cytoplasm

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:4daj, PDBe:4daj, PDBj:4daj
PDBsum4daj
PubMed22358844
UniProtP00720|ENLYS_BPT4 Endolysin (Gene Name=E);
P08483

[Back to BioLiP]