Structure of PDB 4d8f Chain A

Receptor sequence
>4d8fA (length=327) Species: 813 (Chlamydia trachomatis) [Search protein sequence]
LVPRGSHMQADILDGKQKRVNLNSKRLVNCNQVDVNQLVPIKYKWAWEHY
LNGCANNWLPTEIPMGKDIELWKSDRLSEDERRVILLNLGFFSTAESLVG
NNIVLAIFKHVTNPEARQYLLRQAFEEAVHTHTFLYICESLGLDEKEIFN
AYNERAAIKAKDDFQMEITGKVLDPNFRTDSVEGLQEFVKNLVGYYIIME
GIFFYSGFVMILSFHRQNKMIGIGEQYQYILRDETIHLNFGIDLINGIKE
ENPEIWTPELQQEIVELIKRAVDLEIEYAQDCLPRGILGLRASMFIDYVQ
HIADRRLERIGLKPIYHTKNPFPWMSE
3D structure
PDB4d8f Evidence that the beta subunit of Chlamydia trachomatis ribonucleotide reductase is active with the manganese ion of its manganese(IV)/iron(III) cofactor in site 1.
ChainA
Resolution2.2 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) F127 D226
Catalytic site (residue number reindexed from 1) F134 D233
Enzyme Commision number 1.17.4.1: ribonucleoside-diphosphate reductase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FE A E120 E193 E227 H230 E127 E200 E234 H237
BS02 MN A E89 E120 H123 E227 E96 E127 H130 E234
Gene Ontology
Molecular Function
GO:0004748 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor
GO:0016491 oxidoreductase activity
GO:0046872 metal ion binding
Biological Process
GO:0009263 deoxyribonucleotide biosynthetic process

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Molecular Function
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Biological Process
External links
PDB RCSB:4d8f, PDBe:4d8f, PDBj:4d8f
PDBsum4d8f
PubMed22242660
UniProtO84835|RIR2_CHLTR Ribonucleoside-diphosphate reductase subunit beta (Gene Name=nrdB)

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