Structure of PDB 4d7n Chain A

Receptor sequence

>4d7nA (length=195) Species: 562 (Escherichia coli)

SRLNRESVIDAALELLNETGIDGLTTRKLAQKLGIEQPTLYWHVKNKRAL
LDALAVEILARHHDYSLPAAGESWQSFLRNNAMSFRRALLRYRDGAKVHL
GTRPDEKQYDTVETQLRFMTENGFSLRDGLYAISAVSHFTLGAVLEQQEH
TNLPPLLREALQIMDSDDGEQAFLHGLESLIRGFEVQLTALLQIV

3D structure

• PDB: 4d7n Tetracycline Repressor Allostery Does not Depend on Divalent Metal Recognition.
• Chain: A
• Resolution: 1.76 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	TDC	A	H64 N82 F86 H100 P105 Q116 I134 S138 V208	H63 N81 F85 H99 P104 Q115 I133 S137 V195	MOAD: Ka=23000000M^-1
BS02	K	A	H100 T103 R104 P105	H99 T102 R103 P104

Gene Ontology

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UnboundLocalError

Python 3.6.8: /usr/bin/python3 Wed Feb 26 07:54:41 2025

A problem occurred in a Python script. Here is the sequence of function calls leading up to the error, in the order they occurred.

 /var/www/html/BioLiP/pdb.cgi in <module>()

   1443                 pubmed=display_regular_ligand(pdbid,asym_id,lig3,ligIdx,title)

   1444         else:

=> 1445             pubmed,uniprot=display_protein_receptor(pdbid,asym_id,title)

   1446     

   1447     uniprot_line=''

pubmed = '', uniprot = '', display_protein_receptor = <function display_protein_receptor>, pdbid = '4d7n', asym_id = 'A', title = 'Tetracycline Repressor Allostery Does not Depend on Divalent Metal Recognition.'

 /var/www/html/BioLiP/pdb.cgi in display_protein_receptor(pdbid='4d7n', asym_id='A', title='Tetracycline Repressor Allostery Does not Depend on Divalent Metal Recognition.')

    839 

    840     if go:

=>  841         display_go(go,uniprot,pdbid,asym_id)

    842     return pubmed,uniprot

    843 

global display_go = <function display_go>, go = '0003677,0045892,0046677', uniprot = '', pdbid = '4d7n', asym_id = 'A'

 /var/www/html/BioLiP/pdb.cgi in display_go(go='0003677,0045892,0046677', uniprot='', pdbid='4d7n', asym_id='A')

    480         '''.replace("$namespace_link",namespace_link

    481           ).replace("$namespace",namespace

=>  482           ).replace("$uniprot",u

    483         ))

    484         for l,(term,name) in enumerate(go2aspect[Aspect]):

u undefined

UnboundLocalError: local variable 'u' referenced before assignment
      args = ("local variable 'u' referenced before assignment",)
      with_traceback = <built-in method with_traceback of UnboundLocalError object>