Structure of PDB 4d52 Chain A

Receptor sequence
>4d52A (length=314) [Search protein sequence]
STPGAQQVLFRTGIAAVNSTNHLRVYFQDVYGSIRESLYEGSWANGTEKN
VIGNAKLGSPVAATSKELKHIRVYTLTEGNTLQEFAYDSGTGWYNGGLGG
AKFQVAPYSCIAAVFLAGTDALQLRIYAQKPDNTIQEYMWNGDGWKEGTN
LGGALPGTGIGATSFRYTDYNGPSIRIWFQTDDLKLVQRAYDPHKGWYPD
LVTIFDRAPPRTAIAATSFGAGNSSIYMRIYFVNSDNTIWQVCWDHGKGY
HDKGTITPVIQGSEVAIISWGSFANNGPDLRLYFQNGTYISAVSEWVWNR
AHGSQLGRSALPPA
3D structure
PDB4d52 Structural Insights Into Aspergillus Fumigatus Lectin Specificity: Afl Binding Sites are Functionally Non-Equivalent.
ChainA
Resolution1.76 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GXL A R25 E37 L69 Y88 R24 E36 L68 Y87 PDBbind-CN: -logKd/Ki=3.11,Kd=775uM
BS02 GIV A R25 E37 L69 Y88 R24 E36 L68 Y87 PDBbind-CN: -logKd/Ki=3.11,Kd=775uM
BS03 GXL A R73 E85 G98 L125 W141 W146 R72 E84 G97 L124 W140 W145 PDBbind-CN: -logKd/Ki=3.11,Kd=775uM
BS04 GXL A R126 E138 T150 I176 Y192 W198 R125 E137 T149 I175 Y191 W197 PDBbind-CN: -logKd/Ki=3.11,Kd=775uM
BS05 GXL A Y40 R282 E296 Y39 R281 E295 PDBbind-CN: -logKd/Ki=3.11,Kd=775uM
BS06 GIV A R126 E138 M140 T150 I176 Y192 W198 R125 E137 M139 T149 I175 Y191 W197 PDBbind-CN: -logKd/Ki=3.11,Kd=775uM
BS07 GIV A Y40 R282 E296 Y39 R281 E295 PDBbind-CN: -logKd/Ki=3.11,Kd=775uM
Gene Ontology
Molecular Function
GO:0030246 carbohydrate binding
GO:0046872 metal ion binding
Biological Process
GO:0008150 biological_process

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:4d52, PDBe:4d52, PDBj:4d52
PDBsum4d52
PubMed25760594
UniProtQ4WW81|LECF_ASPFU Fucose-specific lectin (Gene Name=fleA)

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