Structure of PDB 4d2c Chain A

Receptor sequence
>4d2cA (length=429) Species: 264199 (Streptococcus thermophilus LMG 18311) [Search protein sequence]
KTFFGQPLGLSTLFMTEMWERFSYYGMRAILLYYMWFLISTGDLHITRAT
AASIMAIYASMVYLSGTIGGFVADRIIGARPAVFWGGVLIMLGHIVLALP
FGASALFGSIILIIIGTGFLKPNVSTLVGTLYDEHDRRRDAGFSIFVFGI
NLGAFIAPLIVGAAQEAAGYHVAFSLAAIGMFIGLLVYYFGGKKTLDPHY
LRPTDPLAPEEVKPLLVKVSLAVAGFIAIIVVMNLVGWNSLPAYINLLTI
VAIAIPVFYFAWYIPLFIAAVLFWAIEEQGSVVLATFAAERVDSSWFPVS
WFQSLNPLFIMLYTPFFAWLWTAWSSPTKFAVGLMFAGLSFLLMAIPGAL
YGTSGKVSPLWLVGSWALVILGEMLISPVMMSMWFLSSSVGSALNAQLVT
LYNAKSEVAYFSYFGLGSVVLGIVLVFLS
3D structure
PDB4d2c Structural Basis for Polyspecificity in the Pot Family of Proton-Coupled Oligopeptide Transporters.
ChainA
Resolution2.47 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 78M A R85 P86 F89 Y194 K198 R80 P81 F84 Y189 K193
BS02 78M A A248 I255 A243 I250
BS03 78N A L369 I373 A376 L342 I346 A349
BS04 78M A L370 S385 L387 W388 G391 L343 S358 L360 W361 G364
BS05 78N A F76 I81 L212 F71 I76 L207
BS06 ALA A N156 N328 N151 N306
BS07 PHE A R26 Y30 I155 W427 R21 Y25 I150 W384
Gene Ontology
Molecular Function
GO:0022857 transmembrane transporter activity
GO:0042802 identical protein binding
GO:1904680 peptide transmembrane transporter activity
Biological Process
GO:0006857 oligopeptide transport
GO:0015833 peptide transport
GO:0055085 transmembrane transport
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4d2c, PDBe:4d2c, PDBj:4d2c
PDBsum4d2c
PubMed24916388
UniProtQ5M4H8

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