Structure of PDB 4d0e Chain A

Receptor sequence
>4d0eA (length=122) Species: 9606 (Homo sapiens) [Search protein sequence]
DVDECSLGANPCEHAGKCINTLGSFECQCLQGYTGPRCEIDVNECVSNPC
QNDATCLDQIGEFQCICMPGYEGVHCEVNTDECASSPCLHNGRCLDKINE
FQCECPTGFTGHLCQVDLHHIL
3D structure
PDB4d0e Fringe-Mediated Extension of O-Linked Fucose in the Ligand-Binding Region of Notch1 Increases Binding to Mammalian Notch Ligands.
ChainA
Resolution1.61 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FUC A T466 C478 M479 T55 C67 M68
BS02 CA A D452 V453 E455 D469 Q470 D41 V42 E44 D58 Q59
BS03 CA A N490 T491 E493 D507 K508 N79 T80 E82 D96 K97
BS04 CA A D412 V413 E415 N431 T432 S435 D1 V2 E4 N20 T21 S24
BS05 CA A E511 H523 E100 H112
Gene Ontology
Molecular Function
GO:0005509 calcium ion binding

View graph for
Molecular Function
External links
PDB RCSB:4d0e, PDBe:4d0e, PDBj:4d0e
PDBsum4d0e
PubMed24803430
UniProtP46531|NOTC1_HUMAN Neurogenic locus notch homolog protein 1 (Gene Name=NOTCH1)

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