Structure of PDB 4cuk Chain A

Receptor sequence
>4cukA (length=330) Species: 90370 (Salmonella enterica subsp. enterica serovar Typhi) [Search protein sequence]
MKLAVYSTKQYDKKYLQQVNEAFGFELEFFDFLLTEKTAKTANGCEAVCI
FVNDDGSRPVLEELKKHGVKYIALRCAGFNNVDLDAAKELGLQVVRVPAY
SPEAVAEHAIGMMMTLNRRIHRAYQRTRDANFSLEGLTGFTMHGKTAGVI
GTGKIGVAALRILKGFGMRLLAFDPYPSTAALDLGVEYVDLQTLFAESDV
ISLHCPLTPENYHLLNHAAFDQMKNGVMIINTSRGALIDSQAAIEALKNQ
KIGSLGMDVYENERDLFFEDKSVDVIQDDVFRRLSACHNVLFTGHQAFLT
AEALISISETTLQNLSQLEKGEACPNALFK
3D structure
PDB4cuk The Structure of Salmonella D-Lactate Dehydrogenase
ChainA
Resolution2.18 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) S101 R234 D258 E263 H295
Catalytic site (residue number reindexed from 1) S101 R234 D258 E263 H295
Enzyme Commision number 1.1.1.28: D-lactate dehydrogenase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 NAI A Y100 G153 K154 I155 F173 D174 P175 H204 C205 P206 N211 T232 Y260 H295 A297 Y100 G153 K154 I155 F173 D174 P175 H204 C205 P206 N211 T232 Y260 H295 A297
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0008720 D-lactate dehydrogenase activity
GO:0016491 oxidoreductase activity
GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
GO:0051287 NAD binding
Cellular Component
GO:0005829 cytosol

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Molecular Function
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Cellular Component
External links
PDB RCSB:4cuk, PDBe:4cuk, PDBj:4cuk
PDBsum4cuk
PubMed
UniProtQ8Z780

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