Structure of PDB 4cuc Chain A

Receptor sequence
>4cucA (length=847) Species: 170187 (Streptococcus pneumoniae TIGR4) [Search protein sequence]
AVTNEEVNQMIEDRKVDFNQNWYFKLNANSKEAIKPDADVSTWKKLDLPY
DWSIFNDFDHESPAQNEGGQLNGGEAWYRKTFKLDEKDLKKNVRLTFDGV
YMDSQVYVNGQLVGHYPNGYNQFSYDITKYLQKDGRENVIAVHAVNKQPS
SRWYSGSGIYRDVTLQVTDKVHVEKNGTTILTPKLEEQQHGKVETHVTSK
IVNTDDKDHELVAEYQIVERGGHAVTGLVRTASRTLKAHESTSLDAILEV
ERPKLWTVLNDKPALYELITRVYRDGQLVDAKKDLFGYRYYHWTPNEGFS
LNGERIKFHGVSLHHDHGALGAEENYKAEYRRLKQMKEMGVNSIRTTHNP
ASEQTLQIAAELGLLVQEEAFDTWYGGKKPYDYGRFFEKDATHPEARKGE
KWSDFDLRTMVERGKNNPAIFMWSIGNEIGEANGDAHSLATVKRLVKVIK
DVDKTRYVTMGADKFRFGNGSGGHEKIADELDAVGFNYSEDNYKALRAKH
PKWLIYGSQTSSATRTRGSYYRPERELKHSNGPERNYEQSDYGNDRVGWG
KTATASWTFDRDNAGYAGQFIWTGTDYIGEPTPWHNQNQTPVKSSYFGIV
DTAGIPKHDFYLYQSQWVSVKKKPMVHLLPHWNWENKELASKVADSEGKI
PVRAYSNASSVELFLNGKSLGLKTFNKKQTSDGRTYQEGANANELYLEWK
VAYQPGTLEAIARDESGKEIARDKITTAGKPAAVRLIKEDHAIAADGKDL
TYIYYEIVDSQGNVVPTANNLVRFQLHGQGQLVGVDNGEQASRERYKAQA
DGSWIRKAFNGKGVAIVKSTEQAGKFTLTAHSDLLKSNQVTVFTGKK
3D structure
PDB4cuc Unravelling the Multiple Functions of the Architecturally Intricate Streptococcus Pneumoniae Beta-Galactosidase, BgaA.
ChainA
Resolution2.2 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) R288 H450 H484 T509 Y511 E564 Y629 Q645 S730 F733
Catalytic site (residue number reindexed from 1) R152 H314 H348 T373 Y375 E428 Y493 Q509 S594 F597
Enzyme Commision number 3.2.1.23: beta-galactosidase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GAL A E564 Q645 W708 E716 T718 E428 Q509 W572 E580 T582
Gene Ontology
Molecular Function
GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds
Biological Process
GO:0005975 carbohydrate metabolic process

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:4cuc, PDBe:4cuc, PDBj:4cuc
PDBsum4cuc
PubMed25210925
UniProtA0A0H2UP19

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