Structure of PDB 4css Chain A

Receptor sequence
>4cssA (length=155) Species: 83333 (Escherichia coli K-12) [Search protein sequence]
FACKTANGTAIPIGGGSANVYVNLAPVVNVGQNLVVDLSTQIFCHNDYPE
TITDYVTLQRGSAYGGVLSNFSGTVKYSGSSYPFPTTSETPRVVYNSRTD
KPWPVALYLTPVGGVAIKAGSLIAVLILRQTNNYNSDDFQFVWNIYANND
VVVPT
3D structure
PDB4css Fimh Antagonists: Bioisosteres to Improve the in Vitro and in Vivo Pk/Pd Profile.
ChainA
Resolution1.069 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CWX A F1 I13 N46 D47 Y48 I52 D54 Q133 N135 D140 F1 I13 N46 D47 Y48 I52 D54 Q130 N132 D137 MOAD: Kd=3.5nM
PDBbind-CN: -logKd/Ki=8.46,Kd=3.5nM
Gene Ontology
Cellular Component
GO:0009289 pilus

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Biological Process
View graph for
Cellular Component
External links
PDB RCSB:4css, PDBe:4css, PDBj:4css
PDBsum4css
PubMed25666045
UniProtP08191|FIMH_ECOLI Type 1 fimbrin D-mannose specific adhesin (Gene Name=fimH)

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