Structure of PDB 4com Chain A

Receptor sequence
>4comA (length=601) Species: 243274 (Thermotoga maritima MSB8) [Search protein sequence]
MKVQYSFEREFEELMSDLLSKYGYEMFQMDGLGDQLDVVKFTEDFVRRGV
TNISTYFIEISKPHTYLYSLYRIWQKMKEMFGKGVADEFVEAQINGAVYL
HDRHHAALMPYCFAYTLKPIVEKGLPFIKTIKSEPAKHLSTFIQHVIQFV
MFASNQSSGAVGLPDFFVWMWYFVKKDLKEGIIPRDKLDWYIEQHFQILT
YSLNQPIRTTQSPYTNFTYLDRNYIKAIFEGERYPDGSLITDHVEDIIAL
QKHYWEWVSRERERQMFTFPVLTASLLYKDGKFLDEDSARFINKINMKWQ
DTNWYISDSIDAVASCCEKLKGRMNSIGGSDLNIGSFKVITVNLPRIALE
SGGDREKYLQILRHRVQLIKKALAAVREIIKERISEGLLPLYENGLMLLN
RQYGTIGVTGVWESASIMGLTTEDIDGLKYTEEGEVFVDNVLDTIREEAE
KGYHEYGFTFNIEQVPAEKAAVTLAQKDRFLFGEKQPFEIYSNQWVPLMA
NTDVLNRIRYSGKWDKKVSGGAILHINLGESFKTEEESFNMVKMIADMGV
MYFAFNTKISVCEDGHAFYGERCPVCGKAKVDEYMRIVGYLVPVSAFNKE
R
3D structure
PDB4com The Crystal Structure of Thermotoga Maritima Class III Ribonucleotide Reductase Lacks a Radical Cysteine Pre-Positioned in the Active Site.
ChainA
Resolution1.92 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.17.4.2: ribonucleoside-triphosphate reductase (thioredoxin).
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN A C594 H598 C605 C562 H566 C573
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0004748 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor
GO:0008998 ribonucleoside-triphosphate reductase (thioredoxin) activity
GO:0016491 oxidoreductase activity
GO:0046872 metal ion binding
Biological Process
GO:0006260 DNA replication
GO:0009265 2'-deoxyribonucleotide biosynthetic process
Cellular Component
GO:0031250 anaerobic ribonucleoside-triphosphate reductase complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4com, PDBe:4com, PDBj:4com
PDBsum4com
PubMed26147435
UniProtQ9WYL6

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