Structure of PDB 4cnf Chain A

Receptor sequence
>4cnfA (length=155) Species: 2285 (Sulfolobus acidocaldarius) [Search protein sequence]
MTIRLVIVEPEGAYNLGFIARLVKNFLIDEFYVVNPKADINEAIKFSAKG
SEVIEKMMKITNNFDDAIRDVDLKIATSSIADGDLLRKSIRPIDLERLIK
DKKVAFIFGRESVGLTREEIAKSDFLLFIPANPEYPVLNLSHAVGIVLYE
LWRNR
3D structure
PDB4cnf Characterization of Two Homologous 2'-O-Methyltransferases Showing Different Specificities for Their tRNA Substrates.
ChainA
Resolution1.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.1.1.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MTA A T77 S78 S79 F110 G111 I131 L140 A145 T77 S78 S79 F108 G109 I129 L138 A143
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0008168 methyltransferase activity
GO:0008173 RNA methyltransferase activity
Biological Process
GO:0002128 tRNA nucleoside ribose methylation
GO:0006396 RNA processing
GO:0008033 tRNA processing
GO:0032259 methylation
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4cnf, PDBe:4cnf, PDBj:4cnf
PDBsum4cnf
PubMed24951554
UniProtQ4JB16|TRMJ_SULAC tRNA (cytidine-2'-O-)-methyltransferase TrmJ (Gene Name=trmJ)

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