Structure of PDB 4cim Chain A

Receptor sequence
>4cimA (length=146) Species: 9606 (Homo sapiens) [Search protein sequence]
APDTRALVADFVGYKLRQKGYVSGAGPGEGPAADPLGQALRAIGDEFETR
FRRTFSDLAAQLHVTPGSAQQRFTQVSDELFQGGPNWGRLVAFFVFGAAL
CAESVNKEMEPLVGQVQEWMVEYLETRLADWIHSSGGWAEFTALYG
3D structure
PDB4cim The Functional Differences of Pro-Survival and Pro-Apoptotic B Cell Lymphoma 2 (Bcl-2) Proteins Depend on Structural Differences in Their Bcl-2 Homology 3 (Bh3) Domains
ChainA
Resolution1.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A I49 E52 F53 R56 F57 F61 R78 V82 E85 L86 N92 W93 G94 R95 Y151 I43 E46 F47 R50 F51 F55 R72 V76 E79 L80 N86 W87 G88 R89 Y145
Gene Ontology
Biological Process
GO:0042981 regulation of apoptotic process

View graph for
Biological Process
External links
PDB RCSB:4cim, PDBe:4cim, PDBj:4cim
PDBsum4cim
PubMed25371206
UniProtQ92843|B2CL2_HUMAN Bcl-2-like protein 2 (Gene Name=BCL2L2)

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