Structure of PDB 4chi Chain A

Receptor sequence
>4chiA (length=320) Species: 330879 (Aspergillus fumigatus Af293) [Search protein sequence]
ASMDKVFSGYYARQKLLERSDNPFSKGIAYVEGKLVLPSDARIPLLDEGF
MHSDLTYDVISVWDGRFFRLDDHLQRILESCDKMRLKFPLALSSVKNILA
EMVAKSGIRDAFVEVIVTRGLTGVRGSKPEDLYNNNIYLLVLPYIWVMAP
ENQLHGGEAIITRTVRRTPPGAFDPTIKNLQWGDLTKGLFEAMDRGATYP
FLTDGDTNLTEGSGFNIVLVKNGIIYTPDRGVLRGITRKSVIDVARANSI
DIRLEVVPVEQAYHSDEIFMCTTAGGIMPITLLDGQPVNDGQVGPITKKI
WDGYWEMHYNPAYSFPVDYG
3D structure
PDB4chi Crystallographic Characterization of the (R)-Selective Amine Transaminase from Aspergillus Fumigatus.
ChainA
Resolution1.27 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) Y58 K179 E212 L234
Catalytic site (residue number reindexed from 1) Y57 K178 E211 L233
Enzyme Commision number 2.6.1.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 PLP A R77 K179 E212 F216 L234 G236 I237 T238 T273 T274 R76 K178 E211 F215 L233 G235 I236 T237 T272 T273
BS02 PO4 A R77 G236 I237 T238 T274 R76 G235 I236 T237 T273
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0008483 transaminase activity
Biological Process
GO:0019752 carboxylic acid metabolic process
GO:0046394 carboxylic acid biosynthetic process
Cellular Component
GO:0005575 cellular_component

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4chi, PDBe:4chi, PDBj:4chi
PDBsum4chi
PubMed24699652
UniProtQ4WH08

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