Structure of PDB 4ch5 Chain A

Receptor sequence
>4ch5A (length=263) Species: 192952 (Methanosarcina mazei Go1) [Search protein sequence]
PALTKSQTDRLEVLLNPKDEISLNSGKPFRELESELLSRRKKDLQQIYAE
ERENYLGKLEREITRFFVDRGFLEIKSPILIPLEYIERMGIDNDTELSKQ
IFRVDKNFCLRPMLAPNLYNYLRKLDRALPDPIKIFEIGPCYRKESDGKE
HLEEFTMLNFCQMGSGCTRENLESIITDFLNHLGIDFKIVGDYGDTLDVM
HGDLELSSAVVGPIPLDREWGIDKPWIGAGFGLERLLKVKHDFKNIKRAA
RSESYYNGISTNL
3D structure
PDB4ch5 Structural Basis for the Site-Specific Incorporation of Lysine Derivatives Into Proteins.
ChainA
Resolution2.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 6.1.1.26: pyrrolysine--tRNA(Pyl) ligase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 YLP A R330 E332 H338 L339 F342 M344 N346 E396 L397 S398 S399 W417 G421 G423 R426 R143 E145 H151 L152 F155 M157 N159 E205 L206 S207 S208 W226 G230 G232 R235
BS02 POP A R330 H338 E396 R426 R143 H151 E205 R235
Gene Ontology
Molecular Function
GO:0000049 tRNA binding
GO:0004812 aminoacyl-tRNA ligase activity
GO:0005524 ATP binding
Biological Process
GO:0043039 tRNA aminoacylation

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Molecular Function
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Biological Process
External links
PDB RCSB:4ch5, PDBe:4ch5, PDBj:4ch5
PDBsum4ch5
PubMed24760130
UniProtQ8PWY1|PYLS_METMA Pyrrolysine--tRNA ligase (Gene Name=pylS)

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