Structure of PDB 4cd1 Chain A

Receptor sequence
>4cd1A (length=406) Species: 10116 (Rattus norvegicus) [Search protein sequence]
LKYGIVLDAGSSHTSMFVYKWPADKENDTGIVGQHSSCDVQGGGISSYAN
DPSKAGQSLVRCLEQALRDVPRDRHASTPLYLGATAGMRLLNLTSPEATA
RVLEAVTQTLTQYPFDFRGARILSGQDEGVFGWVTANYLLENFIKYGWVG
RWIRPRKGTLGAMDLGGASTQITFETTSPSEDPGNEVHLRLYGQHYRVYT
HSFLCYGRDQILLRLLASALQIHRFHPCWPKGYSTQVLLQEVYQSPCTMG
QAIVSLSGTSNATLCRDLVSRLFNISSCPFSQCSFNGVFQPPVAGNFIAF
SAFYYTVDFLTTVMGLPVGTLKQLEEATEITCNQTWTELQARVPGQKTRL
ADYCAVAMFIHQLLSRGYHFDERSFREVVFQKKAADTAVGWALGYMLNLT
NLIPAD
3D structure
PDB4cd1 Crystal Structure of Ntpdase2 in Complex with the Sulfoanthraquinone Inhibitor Psb-071.
ChainA
Resolution2.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.1.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 8E9 A H50 R245 L249 K392 T393 R394 Y398 H13 R208 L212 K347 T348 R349 Y353 PDBbind-CN: -logKd/Ki=4.89,Ki=12.8uM
BS02 8E9 A D76 S346 Y350 Y398 D39 S301 Y305 Y353 PDBbind-CN: -logKd/Ki=4.89,Ki=12.8uM
Gene Ontology
Molecular Function
GO:0016787 hydrolase activity

View graph for
Molecular Function
External links
PDB RCSB:4cd1, PDBe:4cd1, PDBj:4cd1
PDBsum4cd1
PubMed24462745
UniProtO35795|ENTP2_RAT Ectonucleoside triphosphate diphosphohydrolase 2 (Gene Name=Entpd2)

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