Structure of PDB 4cbx Chain A

Receptor sequence
>4cbxA (length=358) Species: 5821 (Plasmodium berghei) [Search protein sequence]
SIALVVDNGSGMVKSGLAGDDAPKCVFPSIIGIPKECYVGDEAQNKRGIL
TLKYPIEHGIVTNWDDMEKIWRHTFFNELRVSPEEHPVLLTEAPLNPKTN
REKMTQIMFESFDVPAMYVSIQAILSLYASGRTTGIVLDSGDGVTHTVPI
YEGYVLPHAINRTDMAGRDLTYYMMKLFTERGYTFTTTAEREIVRDIKEK
LCYIALDYDEELKKSEERTEEVEEMYELPDGNLITVGSERFRCPEALFNP
SLIGRECPGLHITAYQSIMKCDIDIRKELYNNIVLSGGTTMYNYIGERLT
NEMTSLAPPSMKIKVIAPPERKYSVWIGGSILSSLSTFQKMWITKEEYDE
SGPSIVHR
3D structure
PDB4cbx Structural Differences Explain Diverse Functions of Plasmodium Actins.
ChainA
Resolution2.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.4.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ATP A G13 S14 G15 K18 G156 D157 G158 V159 G182 K213 E214 G302 G303 M306 Y307 G9 S10 G11 K14 G141 D142 G143 V144 G167 K198 E199 G287 G288 M291 Y292
Gene Ontology
Molecular Function
GO:0005524 ATP binding
GO:0016787 hydrolase activity
GO:0016887 ATP hydrolysis activity
Biological Process
GO:0035891 exit from host cell
GO:0044129 positive regulation of development of symbiont in host
GO:0044782 cilium organization
GO:0048232 male gamete generation
Cellular Component
GO:0005737 cytoplasm
GO:0005856 cytoskeleton

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Biological Process
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Cellular Component
External links
PDB RCSB:4cbx, PDBe:4cbx, PDBj:4cbx
PDBsum4cbx
PubMed24743229
UniProtQ4YU79|ACT2_PLABA Actin-2 (Gene Name=ACT2)

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