Structure of PDB 4c7x Chain A

Receptor sequence
>4c7xA (length=662) Species: 362948 (Ligilactobacillus salivarius UCC118) [Search protein sequence]
PYDQVDQLGVNTLRTLSIDAIQRANSGHPGLPMGAAPMAYVLWTRHLKIN
PKTHMNWVNRDRFVLSAGHGSALLYSLAHLAGYDVSMDDLKNFREWKSNT
PGHPEYGCTDGVEATTGPLGQGISMAVGMAMAEAHLGKKFNREGYPVMDH
YTYALIGDGDLMEGVASEAASLAGHLKLGKLIALYDSNGISLDGKTSASF
TENVGARFEAYGWQYILVEDGFNLEEIDKAIVQAKAESDKPTIIEIKTTI
GYGSENQGTHKVHGSPLGEEGVAHAKEVYNWNYPPFTVPEEVSQRFKECL
QDKGVKAENKWNEMFEAYKKEYSDLAQKFSDGFSNKVPNTLGDILPQYGE
DDSIATRAASQKAINALAKEVSSLWGGAADLASSNKTVIAGEGDFQPESY
EGRNIWFGVREFGMACAMNGIMLHGGTRIFGSTFFVFSDYLKAAIRLSAI
QKLPVIYVLTHDSVAVGKDGPTHEPIEQLASLRTIPNVQVFRPADGNETS
AAWKVALETLDKPTILVLSRQNLDTLPISKEKVFDGVEKGGYVVQGAENE
ADGILIATGSEVGLALKAKEELQKKGKDVIVVSLPSWERFEAQSEEYKNT
VIPPELKKRMTIEAGTTYGWAKYAGDHGVMIGIDEFGMSAPSDIVLRELG
MSVENIVDKYLE
3D structure
PDB4c7x High Resolution Crystal Structures of Lactobacillus Salivarius Transketolase in the Presence and Absence of Thiamine Pyrophosphate
ChainA
Resolution2.29 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) H28 I250 H263 E411 H473
Catalytic site (residue number reindexed from 1) H28 I250 H263 E411 H473
Enzyme Commision number 2.2.1.1: transketolase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MG A D158 N188 I190 D158 N188 I190
BS02 TPP A H69 L119 D158 G159 N188 I190 I250 H263 H69 L119 D158 G159 N188 I190 I250 H263
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0004802 transketolase activity
GO:0016740 transferase activity
GO:0046872 metal ion binding
Biological Process
GO:0006098 pentose-phosphate shunt
Cellular Component
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4c7x, PDBe:4c7x, PDBj:4c7x
PDBsum4c7x
PubMed26457526
UniProtQ1WQU8

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