Structure of PDB 4c5p Chain A

Receptor sequence
>4c5pA (length=272) Species: 1781 (Mycobacterium marinum) [Search protein sequence]
DLTGYLDRINYRGATDPTLDVLRDLVSAHTGAIAFENLDPLMGVPVDDLS
AEALADKLVDRRRGGYCYEHNGLIGYVLAELGYRVRRLAGRVVWLAPPDA
PTPAQTHTVLAVTFPGCQGPYLVDVGFGGMTPTAPLRLETGTVQQTALEP
YRLDDRGDGLVLQAMVRDEWQALYEFSTLTRPQVDLRVGSWFVSTHPTSH
FVTGLMAATVADDARWNLMGRNLAIHRRGGTEKILLEDAAAVVDTLGDRF
GINVADVGERGRLEARIDKVCF
3D structure
PDB4c5p Arylamine N-Acetyltransferases from Mycobacteria: Investigations of a Potential Target for Anti- Tubercular Therapy
ChainA
Resolution1.592 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) E39 R65 C70 H110 D127
Catalytic site (residue number reindexed from 1) E36 R62 C67 H107 D124
Enzyme Commision number 2.3.1.5: arylamine N-acetyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 AZI A N220 N225 N217 N222
BS02 AZI A D188 V191 D185 V188
Gene Ontology
Molecular Function
GO:0016407 acetyltransferase activity
GO:0016740 transferase activity

View graph for
Molecular Function
External links
PDB RCSB:4c5p, PDBe:4c5p, PDBj:4c5p
PDBsum4c5p
PubMed
UniProtB2HIZ6

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