Structure of PDB 4byf Chain A

Receptor sequence
>4byfA (length=698) Species: 9606 (Homo sapiens) [Search protein sequence]
DRVGVQDFVLLENFTSEAAFIENLRRRFRENLIYTYIGPVLVSVNPYRDL
QIYSRQHMERYRGVSFYEVPPHLFAVADTVYRALRTERRDQAVMISGESG
AGKTEATKRLLQFYAETCPAPERGGAVRDRLLQSNPVLEAFGNAKTLRND
NSSRFGKYMDVQFDFKGAPVGGHILSYLLEKSRVVHQNHGERNFHIFYQL
LEGGEEETLRRLGLERNPQSYLYLVKGQCAKVSSINDKSDWKVVRKALTV
IDFTEDEVEDLLSIVASVLHLGNIHFAANENAQVTTENQLKYLTRLLSVE
GSTLREALTHRKIELLSPLNLEQAAYARDALAKAVYSRTFTWLVGKINRS
LASKDVESPSWRSTTVLGLLDIYGFEVFQHNSFEQFCINYCNEKLQQLFI
ELTLKSEQEEYEAEGIAWEPVQYFNNKIICDLVEEKFKGIISILDEECLR
PGEATDLTFLEKLEDTVKHHPHFLTHKLADRKSLGRGEFRLLHYAGEVTY
SVTGFLDKNNDLLFRNLKETMCSSKNPIMSQCFDRSEKRPETVATQFKMS
LLQLVEILQSKEPAYVRCIKPNDAKQPGRFDEVLIRHQVKYLGLLENLRV
RRAGFAYRRKYEAFLQRYKSLCPETWPTWAGRPQDGVAVLVRHLGYKPEE
YKMGRTKIFIRFPKTLFATEDALEVRRQSLATKIQAAWRGFHWRQKFL
3D structure
PDB4byf Crystal Structure of Human Myosin 1C-the Motor in Glut4 Exocytosis: Implications for Ca(2+) Regulation and 14-3-3 Binding.
ChainA
Resolution2.74 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) S107 G108 T112 N157 S160 S161 G389 E391
Catalytic site (residue number reindexed from 1) S99 G100 T104 N149 S152 S153 G374 E376
Enzyme Commision number 3.6.4.1: Transferred entry: 5.6.1.8.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MG A T112 S161 T104 S153
BS02 AOV A N53 Y61 S107 G108 G110 K111 T112 E113 N157 S160 S161 Y388 G389 N45 Y53 S99 G100 G102 K103 T104 E105 N149 S152 S153 Y373 G374
Gene Ontology
Molecular Function
GO:0003774 cytoskeletal motor activity
GO:0005524 ATP binding
Cellular Component
GO:0016459 myosin complex

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Molecular Function
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Cellular Component
External links
PDB RCSB:4byf, PDBe:4byf, PDBj:4byf
PDBsum4byf
PubMed24636949
UniProtO00159|MYO1C_HUMAN Unconventional myosin-Ic (Gene Name=MYO1C)

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