Structure of PDB 4by5 Chain A

Receptor sequence
>4by5A (length=171) Species: 7227 (Drosophila melanogaster) [Search protein sequence]
NSKLKQDTIDRLTTDTYFTEKEIRQWHKGFLKDCPNGLLTEQGFIKIYKQ
FFPDGDPSKFASLVFRVFDENNDGAIEFEEFIRALSITSRGNLDEKLHWA
FRLYDVDNDGYITREEMYNIVDAIYQMVGQNTPQKRVDKIFDQMDKNHDD
RLTLEEFREGSKADPRMVQAL
3D structure
PDB4by5 The Guanine-Exchange Factor Ric8A Binds the Calcium Sensor Ncs-1 to Regulate Synapse Number and Probability of Release.
ChainA
Resolution2.22 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CA A D73 N75 D77 A79 E84 D69 N71 D73 A75 E80
BS02 CA A D109 D111 D113 Y115 E120 D105 D107 D109 Y111 E116
BS03 CA A D156 N158 D160 R162 E167 D145 N147 D149 R151 E156
Gene Ontology
Molecular Function
GO:0005509 calcium ion binding
GO:0005515 protein binding
GO:0008048 calcium sensitive guanylate cyclase activator activity
GO:0046872 metal ion binding
Biological Process
GO:0007268 chemical synaptic transmission
GO:0007269 neurotransmitter secretion
GO:0007528 neuromuscular junction development
GO:0016192 vesicle-mediated transport
GO:0046928 regulation of neurotransmitter secretion
Cellular Component
GO:0005737 cytoplasm
GO:0008021 synaptic vesicle

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4by5, PDBe:4by5, PDBj:4by5
PDBsum4by5
PubMed25074811
UniProtQ9VWX8|FRQ2_DROME Frequenin-2 (Gene Name=Frq2)

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