Structure of PDB 4bwx Chain A

Receptor sequence
>4bwxA (length=395) Species: 5141 (Neurospora crassa) [Search protein sequence]
IPKDRRENLQKKLFHMQQLLPNSGLPNLDRWHSLFPLDTKATRNSTCFGY
PSWMYKAQNNKNGRHFALRRIEGYRLTNEKAILNVTKEWKKIINANIVTV
HEAFTTEFFGDSSLIFVYDFHPLSETLYDHHFPPNKIPENLLWSYVCQIA
NALLAIHNAKLAARCLELSKIIWENNRIRLAACSILDVLHHDSPNRKTIE
ELQQEDFVKFGRIILALATNTPTLNFNNIDAALATIVPRYSTQLRGVLEW
LIKPSAPGETKTVETLMPMIGARFANFANFVMQESDEKEFHLMRELENGR
IARLMFKLSVVNERWSETGERLLLKLFRDYVFHQVDADGKARLDTNHYLN
CLSKLDASSEEQILLTSRDNATVFVVSYRSIRQMLDRAYGELGKE
3D structure
PDB4bwx Structure of the Pan3 Pseudokinase Reveals the Basis for Interactions with the Pan2 Deadenylase and the Gw182 Proteins
ChainA
Resolution2.85 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 AGS A L270 D271 M287 R302 H354 S357 E358 T359 S412 K413 I415 L37 D38 M54 R69 H121 S124 E125 T126 S169 K170 I172
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0004672 protein kinase activity
GO:0005524 ATP binding
Biological Process
GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening
GO:0006397 mRNA processing
GO:0006468 protein phosphorylation
Cellular Component
GO:0031251 PAN complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4bwx, PDBe:4bwx, PDBj:4bwx
PDBsum4bwx
PubMed23932717
UniProtQ7SDP4|PAN3_NEUCR PAN2-PAN3 deadenylation complex subunit pan3 (Gene Name=par-2)

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