Structure of PDB 4bwk Chain A

Receptor sequence
>4bwkA (length=392) Species: 5141 (Neurospora crassa) [Search protein sequence]
PKDRRENLQKKLFHMQQLLPNSGLPNLDRWHSLFPLDTKATRNSTCFGYP
SWMYKAQNNKNGRHFALRRIEGYRLTNEKAILNVTKEWKKIINANIVTVH
EAFTTEFFGDSSLIFVYDFHPLSETLYDHHFPPNKIPENLLWSYVCQIAN
ALLAIHNAKLAARCLELSKIIWENNRIRLAACSILDVLHHDSPNRKTIEE
LQQEDFVKFGRIILALATNTPTLNFNNIDAALATIVPRYSTQLRGVLEWL
IKPSAPGETKTVETLLGGITTHLANFANFVMQESDEKEFHLMRELENGRI
ARLMFKLSVVNERETGERLLLKLFRDYVFHQVDADGKARLDTNHYLNCLS
KLDASSEEQILLTSRDNATVFVVSYRSIRQMLDRAYGELGKE
3D structure
PDB4bwk Structure of the Pan3 Pseudokinase Reveals the Basis for Interactions with the Pan2 Deadenylase and the Gw182 Proteins
ChainA
Resolution3.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 AGS A D271 M287 R302 F353 H354 S357 E358 T359 D37 M53 R68 F119 H120 S123 E124 T125
Gene Ontology
Biological Process
GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening
GO:0006397 mRNA processing
Cellular Component
GO:0031251 PAN complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4bwk, PDBe:4bwk, PDBj:4bwk
PDBsum4bwk
PubMed23932717
UniProtQ7SDP4|PAN3_NEUCR PAN2-PAN3 deadenylation complex subunit pan3 (Gene Name=par-2)

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