Structure of PDB 4bwe Chain A

Receptor sequence
>4bweA (length=402) Species: 9606 (Homo sapiens) [Search protein sequence]
SRSCGEVRQIYGAKGFSLSDVPQAEISGEHLRICPQGYTCCTSEMEENLA
NRSHAELETALRDSSRVLQAMLATQLRSFDDHFQHLLNDSERTLQATFPG
AFGELYTQNARAFRDLYSELRLYYRGANLHLEETLAEFWARLLERLFKQL
HLGKQAEALRPFGEAPRELRLRATRAFVAARSFVQGLGVASDVVRKVAQV
PLGPECSRAVMKLVYCAHCLGVPGARPCPDYCRNVLKGCLANQADLDAEW
RNLLDSMVLITDKFWGTSGVESVIGSVHTWLAEAINALQDNRDTLTAAPR
ERPPSGTLEKLVSEAKAQLRDVQDFWISLPGTLCSEKMADDRCWNGMARG
RYLPEVMGDGLANQINNPEVEVDITKPDMTIRQQIMQLKIMTNRLRSAYN
GN
3D structure
PDB4bwe Improvements in the order, isotropy and electron density of glypican-1 crystals by controlled dehydration.
ChainA
Resolution2.46 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CA A I437 E443 I365 E371
BS02 CA A D388 D391 D321 D324
Gene Ontology
Biological Process
GO:0009966 regulation of signal transduction
Cellular Component
GO:0005886 plasma membrane
GO:0062023 collagen-containing extracellular matrix

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Biological Process
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Cellular Component
External links
PDB RCSB:4bwe, PDBe:4bwe, PDBj:4bwe
PDBsum4bwe
PubMed24311593
UniProtP35052|GPC1_HUMAN Glypican-1 (Gene Name=GPC1)

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