Structure of PDB 4bv0 Chain A

Receptor sequence
>4bv0A (length=297) Species: 10116 (Rattus norvegicus) [Search protein sequence]
NSDLDVNTDIYSKVLVTAIYLALFVVGTVGNGVTLFTLARKSRVDYYLGS
LALSDLLILLFALPVDVYNFIWVHHPWAFGDAGCKGYYFLREACTYATAL
NVVSLSVELYLAIRHPLMSRSRTKKFISAIWLASALLAIPMLFTVGLQNL
SGDGTHPGGLVCTPIVDTATLKVVIQLNTFMSFLFPMLVASILNTVIARR
LTVMVHPGRVQALRRGVLVLRAMVIAFVVCWLPYHVRRLMFVYISDEQWT
TALFDFYHYFYMLSNALVYVSAAINPILYNLVSANFRQVFLSTLACL
3D structure
PDB4bv0 Structure of Signaling-Competent Neurotensin Receptor 1 Obtained by Directed Evolution in Escherichia Coli
ChainA
Resolution3.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A D54 L55 D56 H132 Y146 T226 R327 F331 V332 I334 D336 W339 F344 Y347 Y351 D3 L4 D5 H74 Y88 T163 R237 F241 V242 I244 D246 W249 F254 Y257 Y261
Gene Ontology
Molecular Function
GO:0004930 G protein-coupled receptor activity
GO:0016492 G protein-coupled neurotensin receptor activity
Biological Process
GO:0007186 G protein-coupled receptor signaling pathway
Cellular Component
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4bv0, PDBe:4bv0, PDBj:4bv0
PDBsum4bv0
PubMed24453215
UniProtP20789|NTR1_RAT Neurotensin receptor type 1 (Gene Name=Ntsr1)

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