Structure of PDB 4buo Chain A

Receptor sequence
>4buoA (length=304) Species: 10116 (Rattus norvegicus) [Search protein sequence]
NSDLDVNTDIYSKVLVTAIYLALFVVGTVGNSVTLFTLARKKSLQSTVDY
YLGSLALSDLLILLLAMPVELYNFIWVHHPWAFGDAGCRGYYFLRDACTY
ATALNVVSLSVELYLAICHPFKAKTLMSRSRTKKFISAIWLASALLAIPM
LFTMGLQNLSGDGTHPGGLVCTPIVDTATLKVVIQVNTFMSFLFPMLVAS
ILNTVIANKLTVMVHQPGRVQALRRGVLVLRAVVIAFVVCWLPYHVRRLM
FCYISDEQWTTFLFDFYHYFYMLTNALVYVSAAINPILYNLVSANFRQVF
LSTL
3D structure
PDB4buo Structure of Signaling-Competent Neurotensin Receptor 1 Obtained by Directed Evolution in Escherichia Coli
ChainA
Resolution2.75 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A D54 L55 D56 F128 H132 Y146 V224 T226 R327 F331 C332 I334 W339 F344 Y347 D3 L4 D5 F74 H78 Y92 V170 T172 R247 F251 C252 I254 W259 F264 Y267
BS02 GLY A M181 F189 M127 F135
Gene Ontology
Molecular Function
GO:0004930 G protein-coupled receptor activity
GO:0016492 G protein-coupled neurotensin receptor activity
Biological Process
GO:0007186 G protein-coupled receptor signaling pathway
Cellular Component
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4buo, PDBe:4buo, PDBj:4buo
PDBsum4buo
PubMed24453215
UniProtP20789|NTR1_RAT Neurotensin receptor type 1 (Gene Name=Ntsr1)

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