Structure of PDB 4brg Chain A

Receptor sequence
>4brgA (length=359) Species: 446 (Legionella pneumophila) [Search protein sequence]
MDTNPCEKHSCIAVIDAGSTGSRLHIYSYDTDDTNTPIHIEEIWNKKIKP
GFASIQPNSVTIDAYLTMLLADAPIHNIPVYFYATAGMRLLPQSQQKKYY
DELDYWFRQQSQWQLVEAKTITGNDEALFDWLAVNYKLDTLKSVQNKSVG
VMDMGGASVQIVFPMPKNAEISKHNQVELNIYGQNINLYVHSFLGLGQTE
MSHQFLNSPSCFANDYPLPDGESGQGNAPSCKEEVTSLMNSVHKVNQQIQ
PLLALNPVNEWYSIGGISNLASSQLFHFENSELTNQSLLQQGDNQICHQQ
WDILNGQYPDDEYLYQYCLLSSYYYALMVDGYGINPNQTIHYIPPEQNLD
WTIGVVLHR
3D structure
PDB4brg Crystallographic Snapshots Along the Reaction Pathway of Nucleoside Triphosphate Diphosphohydrolases
ChainA
Resolution1.45 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.1.5: apyrase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GNP A G51 S52 T53 R56 G189 A190 Q231 G299 N302 Y346 G18 S19 T20 R23 G156 A157 Q198 G266 N269 Y313
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0016787 hydrolase activity
GO:0046872 metal ion binding

View graph for
Molecular Function
External links
PDB RCSB:4brg, PDBe:4brg, PDBj:4brg
PDBsum4brg
PubMed23830739
UniProtQ5ZUA2

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