Structure of PDB 4bqd Chain A

Receptor sequence
>4bqdA (length=78) Species: 9606 (Homo sapiens) [Search protein sequence]
SEEDEEHTIITDTELPPLKLMHSFCAFKADDGPCKAIMKRFFFNIFTRQC
EEFIYGGCEGNQNRFESLEECKKMCTRD
3D structure
PDB4bqd Small Peptides Blocking Inhibition of Factor Xa and Tissue Factor-Factor Viia by Tissue Factor Pathway Inhibitor (Tfpi)
ChainA
Resolution2.48 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide A T12 T14 A27 F28 K29 A30 D31 D32 A37 I38 F44 N45 I46 F47 I55 T11 T13 A26 F27 K28 A29 D30 D31 A36 I37 F43 N44 I45 F46 I54
BS02 peptide A M39 R41 M38 R40
Gene Ontology
Molecular Function
GO:0004867 serine-type endopeptidase inhibitor activity

View graph for
Molecular Function
External links
PDB RCSB:4bqd, PDBe:4bqd, PDBj:4bqd
PDBsum4bqd
PubMed24275667
UniProtP10646|TFPI1_HUMAN Tissue factor pathway inhibitor (Gene Name=TFPI)

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