Structure of PDB 4bqa Chain A

Receptor sequence
>4bqaA (length=132) Species: 9606 (Homo sapiens) [Search protein sequence]
MSFKDYIQERSDPVEQGKPVIPAAVLAGFTGSGPIQLWQFLLELLSDKSC
QSFISWTGDGWEFKLADPDEVARRWGKRKNKPKMNYEKLSRGLRYYYDKN
IIHKTSGKRYVYRFVCDLQNLLGFTPEELHAI
3D structure
PDB4bqa Structural Insights Into the Autoregulation and Cooperativity of the Human Transcription Factor Ets-2.
ChainA
Resolution2.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna A Y414 R419 R422 Y423 Y425 K432 R437 Y438 Y86 R91 R94 Y95 Y97 K104 R109 Y110 PDBbind-CN: Kd=0.3nM
BS02 dna A Q364 L365 W403 K407 K409 M412 K416 R419 Y423 Y424 K427 Q36 L37 W75 K79 K81 M84 K88 R91 Y95 Y96 K99 PDBbind-CN: Kd=0.3nM
Gene Ontology
Molecular Function
GO:0003700 DNA-binding transcription factor activity
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0006355 regulation of DNA-templated transcription
GO:0006357 regulation of transcription by RNA polymerase II

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Molecular Function
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Biological Process
External links
PDB RCSB:4bqa, PDBe:4bqa, PDBj:4bqa
PDBsum4bqa
PubMed25670864
UniProtP15036|ETS2_HUMAN Protein C-ets-2 (Gene Name=ETS2)

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