Structure of PDB 4bpl Chain A

Receptor sequence

>4bplA (length=422) Species: 4530 (Oryza sativa) [Search protein sequence]

SLPAMIGGVYSDDNNLQLEATTQFRKLLSIERSPPIEEVIQSGVVPRFVQ
FLTREDFPQLQFEAAWALTNIASGTSENTKVVIDHGAVPIFVKLLGSSSD
DVREQAVWALGNVAGDSPKCRDLVLANGALLPLLAQLNEHTKLSMLRNAT
WTLSNFCRGKPQPSFEQTRPALPALARLIHSNDEEVLTDACWALSYLSDG
TNDKIQAVIEAGVCPRLVELLLHPSPSVLIPALRTVGNIVTGDDAQTQCI
IDHQALPCLLSLLTQNLKKSIKKEACWTISNITAGNKDQIQAVINAGIIG
PLVNLLQTAEFDIKKEAAWAISNATSGGSHDQIKYLVSEGCIKPLCDLLI
CPDIRIVTVCLEGLENILKVGETDKTLAAGDVNVFSQMIDEAEGLEKIEN
LQSHDNNEIYEKAVKILEAYWM

3D structure

PDB

4bpl Structural Basis of Interaction of Bipartite Nuclear Localization Signal from Agrobacterium Vird2 with Rice Importin-Alpha

Chain

Resolution

2.3 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	peptide	A	S101 E103 W138 N142 A144 S145 G146 T151 Q177 W180 N184 G187 D188 W223 N227 R230 W264 Y268 R306 V312 T313 G314 W349 N353 A356 E388 W391 N395 S398	S29 E31 W66 N70 A72 S73 G74 T79 Q105 W108 N112 G115 D116 W151 N155 R158 W192 Y196 R234 V240 T241 G242 W277 N281 A284 E316 W319 N323 S326

Gene Ontology

	Molecular Function
GO:0061608	nuclear import signal receptor activity

	Biological Process
GO:0006606	protein import into nucleus

	Cellular Component
GO:0005737	cytoplasm

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Molecular Function

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Biological Process

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Cellular Component

External links

PDB	RCSB:4bpl, PDBe:4bpl, PDBj:4bpl
PDBsum	4bpl
PubMed	24503158
UniProt	Q71VM4\|IMA1A_ORYSJ Importin subunit alpha-1a (Gene Name=Os01g0253300)

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