Structure of PDB 4bpj Chain A

Receptor sequence
>4bpjA (length=144) Species: 9606,10090 [Search protein sequence]
EDDLYRQSLEIISRYLREQATGSKGAAGRRALETLRRVGDGVQRNHETAF
QGMLRKLDIKNEDDVKSLSRVMIHVFSDGVTNWGRIVTLISFGAFVAKHL
KTINQESCIEPLAESITDVLVRTKRDWLVKQRGWDGFVEFFHVE
3D structure
PDB4bpj Structure-Guided Rational Design of Alpha/Beta-Peptide Foldamers with High Affinity for Bcl-2 Family Prosurvival Proteins.
ChainA
Resolution1.599 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A H224 F228 M231 L235 V249 V253 D256 N260 G262 R263 T266 F318 F319 H46 F50 M53 L57 V71 V75 D78 N82 G84 R85 T88 F140 F141
Gene Ontology
Biological Process
GO:0042981 regulation of apoptotic process

View graph for
Biological Process
External links
PDB RCSB:4bpj, PDBe:4bpj, PDBj:4bpj
PDBsum4bpj
PubMed23929624
UniProtP97287|MCL1_MOUSE Induced myeloid leukemia cell differentiation protein Mcl-1 homolog (Gene Name=Mcl1);
Q07820|MCL1_HUMAN Induced myeloid leukemia cell differentiation protein Mcl-1 (Gene Name=MCL1)

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