Structure of PDB 4bkm Chain A

Receptor sequence
>4bkmA (length=304) Species: 10090 (Mus musculus) [Search protein sequence]
GMARCERLRGAALRDVLGQAQGVLFDCDGVLWNGERIVPGAPELLQRLAR
AGKNTLFVSNNSRRARPELALRFARLGFAGLRAEQLFSSALCAARLLRQR
LAGVPDPKAYVLGSPALAAELEAVGVTSVGVGPDVLHGDGPSDWLAVPLE
PDVRAVVVGFDPHFSYMKLTKAVRYLQQPDCLLVGTNMDNRLPLENGRFI
AGTGCLVRAVEMAAQRQADIIGKPSPYMFQCITEDFSVDPARTLMVGDRL
ETDILFGHRCGMTTVLTLTGVSSLEEAQAYLTAGQRDLVPHYYVESIADL
MEGL
3D structure
PDB4bkm Evolutionary and Structural Analyses of the Mammalian Haloacid Dehalogenase-Type Phosphatases Aum and Chronophin Provide Insight Into the Basis of Their Different Substrate Specificities.
ChainA
Resolution2.65 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 3.1.3.16: protein-serine/threonine phosphatase.
3.1.3.21: glycerol-1-phosphatase.
3.1.3.48: protein-tyrosine-phosphatase.
3.1.3.74: pyridoxal phosphatase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MG A D25 D27 D247 D26 D28 D248
Gene Ontology
Molecular Function
GO:0016791 phosphatase activity

View graph for
Molecular Function
External links
PDB RCSB:4bkm, PDBe:4bkm, PDBj:4bkm
PDBsum4bkm
PubMed24338473
UniProtP60487|PLPP_MOUSE Chronophin (Gene Name=Pdxp);
Q8CHP8|PGP_MOUSE Glycerol-3-phosphate phosphatase (Gene Name=Pgp)

[Back to BioLiP]