Structure of PDB 4bj3 Chain A

Receptor sequence
>4bj3A (length=183) Species: 9606 (Homo sapiens) [Search protein sequence]
LIDVVVVCDESNSIYPWDAVKNFLEKFVQGLDIGPTKTQVGLIQYANNPR
VVFNLNTYKTKEEMIVATSQTSQYGGDLTNTFGAIQYARKYAYSAASGGR
RSATKVMVVVTDGESHDGSMLKAVIDQCNHDNILRFGIAVLGYLNRNALD
TKNLIKEIKAIASIPTERYFFNVSDWAALLEKA
3D structure
PDB4bj3 An Activating Mutation Reveals a Second Binding Mode of the Integrin Alpha2 I Domain to the Gfoger Motif in Collagens.
ChainA
Resolution3.042 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A N154 I156 Y157 H258 L286 N12 I14 Y15 H116 L144
BS02 peptide A S153 N154 S155 Q215 D219 L220 T221 H258 S11 N12 S13 Q73 D77 L78 T79 H116
BS03 MG A S153 S155 T221 S11 S13 T79
External links
PDB RCSB:4bj3, PDBe:4bj3, PDBj:4bj3
PDBsum4bj3
PubMed23922814
UniProtP17301|ITA2_HUMAN Integrin alpha-2 (Gene Name=ITGA2)

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