Structure of PDB 4biy Chain A

Receptor sequence
>4biyA (length=228) Species: 83333 (Escherichia coli K-12) [Search protein sequence]
AAGASFNQVVTALERMMTSQQRLLSDISHELRTPLTRLQLGTALLRRRSG
ESKELERIETEAQRLDSMINDLLVMSRNQQKNALVSETIKANQLWSEVLD
NAAFEAEQMGKSLTVNFPPGPWPLYGNPNALESALENIVRNALRYSHTKI
EVGFAVDKDGITITVDDDGPGVSPEDREQIFRPFYRTDTGLGLAIVETAI
QQHRGWVKAEDSPLGGLRLVIWLPLYKR
3D structure
PDB4biy Segmental Helical Motions and Dynamical Asymmetry Modulate Histidine Kinase Autophosphorylation.
ChainA
Resolution3.3 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 2.7.13.3: histidine kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ADP A R359 N360 R363 Y364 G390 V391 I399 Y404 T406 T417 G418 G420 L421 R140 N141 R144 Y145 G171 V172 I180 Y185 T187 T189 G190 G192 L193
Gene Ontology
Molecular Function
GO:0000155 phosphorelay sensor kinase activity
GO:0016772 transferase activity, transferring phosphorus-containing groups
Biological Process
GO:0007165 signal transduction
GO:0016310 phosphorylation
Cellular Component
GO:0016020 membrane

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:4biy, PDBe:4biy, PDBj:4biy
PDBsum4biy
PubMed24492262
UniProtP0AE82|CPXA_ECOLI Sensor histidine kinase CpxA (Gene Name=cpxA)

[Back to BioLiP]